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The Science Behind
MLS® Laser Therapy

This FDA-cleared, Class IV technology synchronizes dual wavelengths with continuous and pulsed emissions bringing you the most advanced laser therapy system available on the market today.

Overview of Laser Therapy

The innovative and patented Multiwave Locked System® (MLS) Therapy Laser was developed in an effort to produce an efficient and simultaneous effect on pain, inflammation, and edema, exceeding the limits of traditional LLLT (low power) and concerns of HP (high power) laser therapy. MLS technology delivers therapeutic wavelengths, 808nm (anti-edemic and anti-inflammatory) and 905nm (analgesic). An energetic synergy is created when delivering these wavelengths that produces greater anti-inflammatory and analgesic effects than either can produce on its own, while minimizing the risk of thermal damage. It is this unique combination and synchronization of continuous and pulsed emissions that characterizes MLS and distinguishes it from other Class IV lasers. Unlike early-generation Class IV technology, MLS Laser Therapy has the capability to deliver controlled laser energy. This unique feature provides more accurate therapeutic dose delivery, which means consistent and repeatable results. With high levels of efficacy, safety, and consistency, MLS Laser Therapy can help physicians relieve pain and restore lives, while rewarding their practice financially.
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Illustration of MLS Laser Therapy treating patient's back

What is Laser Therapy?

Laser therapy uses light to favor and accelerate the body’s natural healing processes. The laser beam is moved over the skin so that the light energy (photons) penetrates the tissue where it interacts with various molecules (chromophores) that cause different biological effects. It produces a photochemical, photothermal and photomechanical effect.

There are many types of lasers.  Each laser has different characteristics which produce a different effect.  These characteristics include:

  • Energy: measured in joules
  • Time: Defined as the duration of irradiance of target tissue and is measured in seconds.  It is also known as Impulse Duration or called “impulse width”.
  • Wavelength: Penetration depth is directed by the laser emission wavelength and the type of tissue (chromophores).
  • Frequency: Defined as the number of impulses emitted during the unit of time (1 second) and should reflect the condition treated.
  • Power: the rate at which energy is delivered and is measured in watts.
  • Fluence: Energy Density or Dose
  • Irradiance (Also known as Power Density): Power delivered per unit area
  • Emission Mode: Continuous Wave (CW) or Pulsed Wave (PW)
  • Impulse Duration: Duration of laser emission, also called “impulse width”.

Benefits of MLS® Laser Therapy

No pain. All gain.

In the current economic climate, physicians are facing significant pressure to find new revenue streams. Reimbursements from insurers – the primary source of income for many practices – are declining sharply as a result of political reforms. At the same time, market forces such as increased competition and patient consumerism are adding to the pressure. In this environment, practice owners have limited options for strengthening their financial position. MLS Laser Therapy can help.

MLS Laser Therapy allows physicians to leverage technology to provide higher quality patient care, while attracting new clients, generating additional revenue, and ultimately improving businesses’ bottom line.

Clinical Benefits

MLS Laser Therapy is quickly becoming the standard of care in alleviating both acute and chronic pain. This patented, FDA-cleared technology has an 85% – 90% efficacy rate in relieving pain and inflammation, eliminates risk from surgery and prescription pain killers, has no negative side effects, and restores patients’ lives.

Financial Benefits

Practices benefit financially by:

  • Combating declining reimbursements and generating revenue with a cash-based modality
  • Realizing a rapid return on investment
  • Accelerating patient recoveries
  • Differentiating their practice
  • Increasing patient satisfaction and referrals

Practitioners report that MLS Laser Therapy effectively treats pain and inflammation associated with the following conditions:

  • Plantar Fasciitis
  • Neuromas
  • Neuropathies
  • Arthritis
  • Sports injuries
  • Tendon & ligament injuries
  • Back & joint pain
  • Muscle sprains & strains
  • Tendonitis
  • Wounds
  • Post-surgical swelling
  • Disc disease
MLS Laser Therapy has an anti-edema effect as it causes vasodilation, but also because it activates the lymphatic drainage system which drains swollen areas. As a result, there is a reduction in swelling caused by bruising or inflammation.
MLS Laser Therapy has a beneficial effect on nerve cells. It blocks pain transmitted by these cells to the brain which decreases nerve sensitivity. Also, due to the decreased inflammation, there is less edema and less pain. Another pain blocking mechanism involves the production of high levels of pain killing chemicals such as endorphins and enkephalin from the brain and adrenal glands.
Photons of light from lasers penetrate deeply into tissue and accelerate cellular reproduction and growth. The laser light increases the energy available to the cell so that the cell can take on nutrients faster and get rid of waste products. As a result of exposure to laser light, damaged cells are repaired faster.
Laser light will significantly increase the formation of new capillaries in damaged tissue which speeds up the healing process, closes wounds quickly and reduces scar tissue. Additional benefits include acceleration of angiogenesis, which causes temporary vasodilation and increases the diameter of blood vessels.
MLS Laser Therapy creates higher outputs of specific enzymes, greater oxygen and food particle loads for blood cells.
MLS Laser Therapy stimulates muscle trigger points and acupuncture points on a noninvasive basis providing musculoskeletal pain relief.
MLS Laser Therapy reduces the formation of scar tissue following tissue damage from cuts, scratches, burns or surgery.
Slow recovery of nerve functions in damaged tissue can result in numbness and impaired limbs. Laser light speeds the process of nerve cell reconnection and increases the amplitude of action potentials to optimize muscle healing.
Laser light has a direct effect on immunity status by stimulating immunoglobulins and lymphocytes. Laser emissions are absorbed by chromophores (molecule enzymes) that react to laser light. Upon exposure to the laser, the enzyme flavomononucleotide is activated and starts the production of ATP (adenosinetriphosphate), which is the major carrier of cell energy and the energy source for all chemical reactions in the cells.
Laser light stimulates fibroblast development in damaged tissue. Fibroblasts are the building blocks of collagen, which is the essential protein required to replace old tissue or to repair tissue injuries. As a result, MLS Laser Therapy is effective post surgically and in the treatment of open wounds and burns.

Biological Effects

Primary

Secondary

Laser Classifications

Low Level Laser Therapy (LLLT) Class 3B

These lasers use very low power, are limited to surface biostimulation, and often require many treatment sessions and long treatment times.  Results are only achieved at the end of the treatment cycle, and results are limited because of the use of only one or two wavelengths that are not synchronized.

High Power (HP) Class IV

These lasers were developed with the expectation that greater power corresponded to better efficiency.  On the contrary, unless suitably controlled, high power can thermally damage the treated tissue.  Therefore, the majority of high power lasers cannot operate at their maximum power without causing damage.

Multiwave Locked System (MLS) Class IV

MLS Laser Therapy is a patented emission system created to achieve an efficient and simultaneous effect on pain, contracture, inflammation, and edema within a short period of time.  The patented control system that generates the MLS pulse synchronizes the emissions to achieve optimum results.  Due to this characteristic synchronization, the various therapeutic effects not only take place at the same time, but reciprocally reinforce each other, without the risk of thermal damage.

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Science

The patented MLS pulse was developed as a result of nearly three decades of scientific research that studied the biological and therapeutic effects of different emission components and methods.

The departments of biology at both the University of Turin (Italy) and the University of Padova (Brazil), as well as the Department of Anatomy and the Orthopedic Clinic at the University of Padova have studied and verified the remarkable effectiveness of MLS Laser Therapy.

To read the MLS Scientific Report, click here.

A collection of studies that demonstrate the effectiveness of MLS Laser Therapy can be read here: MLS® Laser Therapy – Innovation is built on results

FDA Clearance

‘Mphi Family’ Diode Lasers – Mphi, Mphi5, Mphi Orange

Cleared via Section 510(k) on November 9, 2011, Number K111901

Conclusion: “The ASA ‘Mphi Family’ Diode Laser is a safe and effective device for the indications specified.”

Indications for Use: “The ASA ‘Mphi Family’ Diode Laser is intended to provide topical heating for the purpose of elevating tissue temperature for the temporary relief of muscle and joint pain and stiffness, arthritis pain, or muscle spasm, the temporary increase in local blood circulation and/or promoting relaxation of muscle.”

‘MLS Family’ Diode Lasers – MLS Mix5, MLS M1, MLS M6

Cleared via Section 510(k) on August 26, 2005, Number K051922

Conclusion: “The ‘MLSFamily’ Diode Laser is a safe and effective device for the indications specified.”

Indications for Use: “The ‘MLS Family’ Diode Laser is intended to provide topical heating for the purpose of elevating tissue temperature for the temporary relief of muscle and joint pain and stiffness, arthritis pain, or muscle spasm, the temporary increase in local blood circulation and/or promoting relaxation of muscle.”

Patent

MLS Laser Therapy is patented.
United States Patent, No. US 8,251,982 B2
Date of Patent: August 28, 2012

Abstract:

“Apparatuses and methods for applying laser energy for therapeutic purposes (e.g., relief of pain and/or inflammation in tissues) are disclosed.  The synchronization of two spatially overlapping energy forms having closely positioned emission axes and particular emission modalities can in many cases provide strengthened or even synergistic effects in the alleviation or treatment of multiple of acute and/or chronic conditions (e.g., pain and inflammation) afflicting a given tissue.  The laser energy forms are characterized in terms of their power levels, activation times, activation periods, pulse durations, pulse periods, wavelengths, and other identified characteristics.

Testimonials

“What we’re finding is that 90% of our patients are achieving almost 90% relief of their symptoms, which is unheard of. It is the very latest in medical technology, and we are proud to offer our patients something no one else can.”
Dr. Ronald S. Lederman, MD
Ronald S. Lederman, MDCenter for Orthopedic Surgery, Sports Medicine & Physical Therapy
“If we can avoid a medication, have a laser treatment that’s non-invasive, no side effects, very limited contraindications … then why not try when the results we’ve been getting are 90% plus?”
Mark Kwartowitz, DO
Mark Kwartowitz, DOCenter for Orthopedic Surgery, Sports Medicine and Physical Therapy
“Without a doubt, the MLS laser has been transformational in our approach to diabetic polyneuropathy and related nerve issues … The traditional treatment of medicine and surgery has now been enhanced with an alternative that is pain-free, easy to use for both the patient and the doctor, and is devoid of side effects.”
Richard P. Jacoby, DPM
Richard P. Jacoby, DPMValley Foot Surgeons & Laser Center
“It’s benefitted our patients because it requires less time for the healing process. And to me, that’s what it’s all about: getting them better as fast as possible and having confidence as a doctor that you’ll improve their quality of life. I had one patient who had five failed back surgeries, and now he looks like he never had pain.”
Andy Barlow, DC, DACNB, FACFN
Andy Barlow, DC, DACNB, FACFNChiropractic Neurology Center of Tupelo
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FAQ

The most common MLS Laser Therapy indications are pain relief, intervertebral disc disease, degenerative joint disease, arthritic conditions, muscular/skeletal system trauma, and inflammatory conditions.

MLS Laser Therapy uses both the 808nm and 905nm wavelengths simultaneously. The 808nm wavelength is delivered using continuous emission while the 905nm wavelength is delivered using pulsed emission.

MLS Laser Therapy uses two wavelengths to overcome the limits of traditional Laser Therapy. Traditional Laser therapy does not deliver both wavelengths in a reinforcing and synchronized fashion. Continuous laser emissions act fast on inflammation, stimulating blood and lymphatic circulation and inducing fast re-absorption of fluid build ups; however they only have a secondary effect on pain, which is diminished after reducing the inflammatory process. Pulsed laser emissions, on the other hand, have a practically immediate effect on pain, since they are able to induce analgesia, interfering with the very transmission of the pain impulse to the higher brain centers, but they are less effective at treating inflammation and edema.

Yes, the FDA has cleared the use of MLS Laser Therapy and it is also patented via the U.S. Patent Office.

MLS Laser Therapy is able to induce strong anti-inflammatory, anti-edema, and analgesic effects simultaneously and within a short period of time. LLLT cannot achieve these results because of the limitations of using one or two wavelengths that are not synchronized. The patented control system that generates the MLS pulse synchronizes the emissions to achieve results previously unattainable. Thanks to this characteristic synchronization, the various therapeutic effects not only take place at the same time but reciprocally reinforce each other.

MLS Stands for Multi-wave Lock System. MLS is the name of the technology used that utilizes the patented combination of wavelengths.

Yes, MLS Lasers are Class IV therapy lasers that utilize our patented MLS technology to deliver controlled laser energy avoiding the risk factor of thermal damage to the tissue.

The depth of penetration varies due to tissue type, but it will penetrate 3-5 cm in most cases.

Results can often been seen after the first treatment. Most conditions have protocols that range from 6-12 treatments. The treatments are cumulative and are delivered 2-3 times per week for 2-3 weeks.

MLS Laser Therapy has been developed and tested following a strict course of biomedical and clinical research. The effectiveness of the combination of the emissions making up the MLS pulse was initially tested in vitro on cellular cultures, then in vivo on animals, and finally by means of controlled clinical trials run by major state-of-the-art health organizations for treating traumatic and degenerative painful diseases.

Clinical Studies

Comparison of the Effects of a Conventional Physiotherapy with Multiwave Locked System Laser Glenohumeral Joint Peritendinitis: A Randomized Trial

This study evaluates the therapeutical effects of MLS® laser and the combined therapy of microwave diathermy and interference current, in patients with glenohumeral joint peritendinitis. The intergroup analysis showed a greater improvement of MLS Laser Therapy in terms of pain reduction at the end of the treatment and at the mid-term follow-up visit.

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