The Science Behind
MLS® Laser Therapy
Overview of Laser Therapy
What is Laser Therapy?
Laser therapy uses light to favor and accelerate the body’s natural healing processes. The laser beam is moved over the skin so that the light energy (photons) penetrates the tissue where it interacts with various molecules (chromophores) that cause different biological effects. It produces a photochemical, photothermal and photomechanical effect.
There are many types of lasers. Each laser has different characteristics which produce a different effect. These characteristics include:
- Energy: measured in joules
- Time: Defined as the duration of irradiance of target tissue and is measured in seconds. It is also known as Impulse Duration or called “impulse width”.
- Wavelength: Penetration depth is directed by the laser emission wavelength and the type of tissue (chromophores).
- Frequency: Defined as the number of impulses emitted during the unit of time (1 second) and should reflect the condition treated.
- Power: the rate at which energy is delivered and is measured in watts.
- Fluence: Energy Density or Dose
- Irradiance (Also known as Power Density): Power delivered per unit area
- Emission Mode: Continuous Wave (CW) or Pulsed Wave (PW)
- Impulse Duration: Duration of laser emission, also called “impulse width”.
Benefits of MLS® Laser Therapy
No pain. All gain.
In the current economic climate, physicians are facing significant pressure to find new revenue streams. Reimbursements from insurers – the primary source of income for many practices – are declining sharply as a result of political reforms. At the same time, market forces such as increased competition and patient consumerism are adding to the pressure. In this environment, practice owners have limited options for strengthening their financial position. MLS Laser Therapy can help.
MLS Laser Therapy allows physicians to leverage technology to provide higher quality patient care, while attracting new clients, generating additional revenue, and ultimately improving businesses’ bottom line.
MLS Laser Therapy is quickly becoming the standard of care in alleviating both acute and chronic pain. This patented, FDA-cleared technology has an 85% – 90% efficacy rate in relieving pain and inflammation, eliminates risk from surgery and prescription pain killers, has no negative side effects, and restores patients’ lives.
Practices benefit financially by:
- Combating declining reimbursements and generating revenue with a cash-based modality
- Realizing a rapid return on investment
- Accelerating patient recoveries
- Differentiating their practice
- Increasing patient satisfaction and referrals
Practitioners report that MLS Laser Therapy effectively treats pain and inflammation associated with the following conditions:
- Plantar Fasciitis
- Sports injuries
- Tendon & ligament injuries
- Back & joint pain
- Muscle sprains & strains
- Post-surgical swelling
- Disc disease
Direct transfer of energy to the biological sublayers (endogenous or exogenic chromophores).
- Enzymatic activation
- Increase in ATP production
- Modulation of cellular metabolism
- Effect on pain perception threshold
- Increase in ATP synthesis
- Increase in the production of RNA
- Increase in cellular proliferation
- Induction of differentiation processes
- Release of growth factors (fibroblasts) and other substances
- Increase in the production of molecules of the extracellular matrix (fibroblasts & condrocytes)
Low Level Laser Therapy (LLLT) Class 3B
These lasers use very low power, are limited to surface biostimulation, and often require many treatment sessions and long treatment times. Results are only achieved at the end of the treatment cycle, and results are limited because of the use of only one or two wavelengths that are not synchronized.
High Power (HP) Class IV
These lasers were developed with the expectation that greater power corresponded to better efficiency. On the contrary, unless suitably controlled, high power can thermally damage the treated tissue. Therefore, the majority of high power lasers cannot operate at their maximum power without causing damage.
Multiwave Locked System (MLS) Class IV
MLS Laser Therapy is a patented emission system created to achieve an efficient and simultaneous effect on pain, contracture, inflammation, and edema within a short period of time. The patented control system that generates the MLS pulse synchronizes the emissions to achieve optimum results. Due to this characteristic synchronization, the various therapeutic effects not only take place at the same time, but reciprocally reinforce each other, without the risk of thermal damage.
The patented MLS pulse was developed as a result of nearly three decades of scientific research that studied the biological and therapeutic effects of different emission components and methods.
The departments of biology at both the University of Turin (Italy) and the University of Padova (Brazil), as well as the Department of Anatomy and the Orthopedic Clinic at the University of Padova have studied and verified the remarkable effectiveness of MLS Laser Therapy.
To read the MLS Scientific Report, click here.
A collection of studies that demonstrate the effectiveness of MLS Laser Therapy can be read here: MLS® Laser Therapy – Innovation is built on results
‘Mphi Family’ Diode Lasers – Mphi, Mphi5, Mphi Orange
Cleared via Section 510(k) on November 9, 2011, Number K111901
Conclusion: “The ASA ‘Mphi Family’ Diode Laser is a safe and effective device for the indications specified.”
Indications for Use: “The ASA ‘Mphi Family’ Diode Laser is intended to provide topical heating for the purpose of elevating tissue temperature for the temporary relief of muscle and joint pain and stiffness, arthritis pain, or muscle spasm, the temporary increase in local blood circulation and/or promoting relaxation of muscle.”
‘MLS Family’ Diode Lasers – MLS Mix5, MLS M1, MLS M6
Cleared via Section 510(k) on August 26, 2005, Number K051922
Conclusion: “The ‘MLSFamily’ Diode Laser is a safe and effective device for the indications specified.”
Indications for Use: “The ‘MLS Family’ Diode Laser is intended to provide topical heating for the purpose of elevating tissue temperature for the temporary relief of muscle and joint pain and stiffness, arthritis pain, or muscle spasm, the temporary increase in local blood circulation and/or promoting relaxation of muscle.”
MLS Laser Therapy is patented.
United States Patent, No. US 8,251,982 B2
Date of Patent: August 28, 2012
“Apparatuses and methods for applying laser energy for therapeutic purposes (e.g., relief of pain and/or inflammation in tissues) are disclosed. The synchronization of two spatially overlapping energy forms having closely positioned emission axes and particular emission modalities can in many cases provide strengthened or even synergistic effects in the alleviation or treatment of multiple of acute and/or chronic conditions (e.g., pain and inflammation) afflicting a given tissue. The laser energy forms are characterized in terms of their power levels, activation times, activation periods, pulse durations, pulse periods, wavelengths, and other identified characteristics.
The most common MLS Laser Therapy indications are pain relief, intervertebral disc disease, degenerative joint disease, arthritic conditions, muscular/skeletal system trauma, and inflammatory conditions.
MLS Laser Therapy uses both the 808nm and 905nm wavelengths simultaneously. The 808nm wavelength is delivered using continuous emission while the 905nm wavelength is delivered using pulsed emission.
MLS Laser Therapy uses two wavelengths to overcome the limits of traditional Laser Therapy. Traditional Laser therapy does not deliver both wavelengths in a reinforcing and synchronized fashion. Continuous laser emissions act fast on inflammation, stimulating blood and lymphatic circulation and inducing fast re-absorption of fluid build ups; however they only have a secondary effect on pain, which is diminished after reducing the inflammatory process. Pulsed laser emissions, on the other hand, have a practically immediate effect on pain, since they are able to induce analgesia, interfering with the very transmission of the pain impulse to the higher brain centers, but they are less effective at treating inflammation and edema.
Yes, the FDA has cleared the use of MLS Laser Therapy and it is also patented via the U.S. Patent Office.
MLS Laser Therapy is able to induce strong anti-inflammatory, anti-edema, and analgesic effects simultaneously and within a short period of time. LLLT cannot achieve these results because of the limitations of using one or two wavelengths that are not synchronized. The patented control system that generates the MLS pulse synchronizes the emissions to achieve results previously unattainable. Thanks to this characteristic synchronization, the various therapeutic effects not only take place at the same time but reciprocally reinforce each other.
MLS Stands for Multi-wave Lock System. MLS is the name of the technology used that utilizes the patented combination of wavelengths.
Yes, MLS Lasers are Class IV lasers with a peak power of 25 watts.
The depth of penetration varies due to tissue type, but it will penetrate 3-5 cm in most cases.
Results can often been seen after the first treatment. Most conditions have protocols that range from 6-12 treatments. The treatments are cumulative and are delivered 2-3 times per week for 2-3 weeks.
MLS Laser Therapy has been developed and tested following a strict course of biomedical and clinical research. The effectiveness of the combination of the emissions making up the MLS pulse was initially tested in vitro on cellular cultures, then in vivo on animals, and finally by means of controlled clinical trials run by major state-of-the-art health organizations for treating traumatic and degenerative painful diseases.
Healing of Leg Diabetic Ulcer Treated with MLS-MiS Laser
This case report observes the efficacy and safety of the MLS Therapy Laser in a case of chronic diabetic ulcer.
MLS Laser Therapy in Wound Healing
The results of these studies show that MLS Laser Therapy induces an increase of NLRP 10, The anti-inflammatory activity can be used to control inflammation and decrease painful symptoms that are frequently present in patients with wounds or ulcers.
Clinical Case Series: The Effect of MLS® Treatment on 30 Patients with Lumbosacral Sciatic Pain.
This clinical case series concludes that MLS Laser therapy is a useful approach for the treatment of lumbosacral sciatic pain and it is able to promote flexibility.
Case Report: Use of MLS Laser Therapy for Management of COVID-19 Infection
This case report describes the application of a Multiwave Locked System (MLS®) laser in the management of a COVID-19 patient.
Doctors in Lowell, Mass., Report Positive Outcomes for Second COVID-19 Patient Treated with Laser Therapy
Scott Sigman, M.D., published a second case report demonstrating positive outcomes for a COVID-19 patient treated with laser therapy.
COVID-19 Pneumonia Patient Shows Significant Improvements Following Laser Treatment at Massachusetts Hospital
Publication in American Journal of Case Reports Demonstrates Potential of Supportive Photobiomodulation Therapy for COVID-19 Patients LOWELL, Mass., Aug. 9, 2020 /PRNewswire/ — Dr. Scott Sigman, principal investigator